Ankara University | Faculty of Pharmacy  
   

 
  Menu
 
  Research Information

Research Areas:
Synthesis of some heterocyclic compounds (benzothiazole, phenylacetamide, benzamide), QSAR, Molecular Modelling

M.Sc. and Ph.D. Thesis Supervisor:
Prof. Dr. Ismail YALCIN

M.Sc. Thesis Subject:
Studies on the Synthesis, Structure Elucidation and Microbiological Activity of Some Novel 2-[4-(4-Substitutedbenzamido / Phenylacetamido)phenyl] Benzothiazole Derivatives

Ph.D. Thesis Subject:
Synthesis, Structure Elucidation, GST Enzyme Inhibitor Activity and Investigation of Activity Mechanistic Dynamics of Some New Benzothiazole Derivatives

International Projects: 

  1. Doga Elci, Kayhan Bolelli, Janet Plavec, Heinz Amenitch, Structural Characterization of a New Potent Hemostatic Device, Central European Research Infrastructure Consortium (CERIC) Project, 20177028, Post Doctoral Researcher, 19.12.2017-present.

National Projects: 

  1. İlkay Yıldız, Esin Akı, İsmail Yalçın, Arzu Atalay, Tuğba Ertan-Bolelli, Kayhan Bolelli, Serap Yılmaz, Sanaz Ataei, Özüm Öztürk, Synthesis and Molecular Modelling of Some New  Antitumoral Heterocyclic Compounds, Research Fund of Ankara University, Grant No: 12B3336002, Project Budget: 264,020.00 TRY, Researcher, 02.01.2012-2015.
  2. İlkay Yıldız, Esin Akı, İsmail Yalçın, Tuğba Ertan-Bolelli, Kayhan Bolelli, Serap Yılmaz, Ayşe Yeşbek-Kaymaz, Synthesis of Some New DNA Topoisomerase Inhibitor Benzothiazole derivatives, Research Fund of Ankara University, Grant No: 11A3336001, Project Budget: 220,157.37 TRY, Researcher, 06.09.2011-2014.
  3. Özlem Temiz-Arpacı, İlkay Yıldız, Betül Tekiner-Gülbaş, Sabiha Alper, Tuğba Ertan, Kayhan Bolelli, Mustafa Arısoy, Ufuk Abbasoğlu, Fatma Kaynak-Onurdağ, Studies on Synthesis, Structure Elucidation and Microbiological Activities of New Some Benzoxazole and Benzothiazole Derivatives, Research Fund of Ankara University, Grant No: 08B3336001, Project Budget: 38,866.36 TRY, Researcher, 01.01.2008-01.07.2010.

Books:

  1. Esin Aki-Yalcin, Ismail Yalcin, Erdem Buyukbingol, Hakan Goker, Ilkay Yildiz, Tunca Gul Altuntas, Gulgun Ayhan-Kilcigil, Meral Tuncbilek, Sibel Suzen, Ozlem Temiz-Arpaci, Canan Kus, Oya Bozdag-Dundar, Zeynep Ates-Alagoz, Betul Tekiner-Gulbas, Mehmet Alp, Meltem Ceylan-Unlusoy, A. Selen Gurkan-Alp, Tugba Ertan-Bolelli, Zuhal Kilic-Kurt, Cigdem Karaaslan, Kayhan Bolelli, Serap Yilmaz, Dilan Konyar, Ozum Ozturk, Fatima Doganc, “Pharmaceutical Chemistry Practices 1-2”, 2nd Ed., Ankara University Printing House, ISBN: 978-605-136-362-2, 30.03.2018. [In Turkish]
  2. Esin Aki-Yalcin, Ismail Yalcin, Erdem Buyukbingol, Hakan Goker, Ilkay Yildiz, Tunca Gul Altuntas, Gulgun Ayhan-Kilcigil, Meral Tuncbilek, Sibel Suzen, Ozlem Temiz-Arpaci, Canan Kus, Oya Bozdag-Dundar, Zeynep Ates-Alagoz, Betul Tekiner-Gulbas, Mehmet Alp, Meltem Ceylan-Unlusoy, A. Selen Gurkan-Alp, Tugba Ertan-Bolelli, Zuhal Kilic-Kurt, Cigdem Karaaslan, Kayhan Bolelli, Serap Yilmaz, Dilan Konyar, Ozum Ozturk, Fatima Doganc, “Pharmaceutical Chemistry Practices 3-4”, 2nd Ed., Ankara University Printing House, ISBN: 978-605-136-363-9, 30.03.2018. [In Turkish]

Publications:

Original Papers

  1. Tugba Ertan-Bolelli, Kayhan Bolelli, Yaman Musdal, Ilkay Yildiz, Esin Aki-Yalcin, Bengt Mannervik, Ismail Yalcin, “Design and Synthesis of 2-Substituted-5-(4-trifluoromethylphenylsulfonamido)benzoxazole Derivatives as Human GST P1-1 Inhibitors”, Artificial Cells, Nanomedicine, and Biotechnology, 46(3), 510-517 (2018). DOI: 10.1080/21691401.2017.1324464
  2. Kayhan Bolelli, Yaman Musdal, Esin Aki-Yalcin, Bengt Mannervik, Ismail Yalcin, “Synthesis and Activity Mechanism of Some Novel 2-Substituted Benzothiazoles as hGSTP1-1 Enzyme Inhibitors”, SAR & QSAR In Environment Research, 28(11), 927-940 (2017). DOI: 10.1080/1062936X.2017.1402820
  3. Ozum Ozturk, Esin Aki-Yalcin, Tugba Ertan-Bolelli, Kayhan Bolelli, Andry Nur Hidayat, Ozlem Bingol-Ozakpinar, Filiz Ozdemir, Ismail Yalcin, “Possible Mechanism of Action of Neurokinin-1 Receptors (NK1R) Antagonists”, Journal of Pharmacy and Pharmacology, 5(11), 787-797 (2017). DOI: 10.17265/2328-2150/2017.11.001
  4. Tugba Ertan-Bolelli, Kayhan Bolelli, Suzan Okten, Fatma Kaynak-Onurdag, Esin Aki-Yalcin, Ismail Yalcin, “Synthesis, Antimicrobial Activities of New Sulfonamidobenzoxazoles and Molecular Docking Studies on Escherichia coli TEM-1 β-Lactamase”, Croatica Chemica Acta, 90(1), 67-74 (2017). DOI: 10.5562/cca3111
  5. Ugur Senel, Tugba Ertan-Bolelli, Kayhan Bolelli, Ilkay Yildiz, "Docking Studies on Enoyl-Acyl Carrier Protein (ACP) Reductase Enzyme Inhibitors", Journal of Faculty of Pharmacy of Ankara University, 45(1), 1-12 (2016). [in Turkish] DOI: 10.1080/21691401.2017.1324464
  6. Emine Oksuzoglu, Egemen Foto, Fatma Zilifdar, Tugba Ertan-Bolelli, Kayhan Bolelli, “Antiproliferative and Genotoxic Activities in L929 and HeLa Cell Lines - the Mutagenic Effects in Salmonella Strains of Novel Benzoxazole Derivatives”, Latin American Journal of Pharmacy, 35(10), 2216-2224 (2016).
  7. Serap Yilmaz, Gulsen Altinkanat-Gelmez, Kayhan Bolelli, Deniz Guneser-Merdan, M. Ufuk Over-Hasdemir, Esin Aki, Ismail Yalcin, "Binding Site Feature Description of 2-Substituted Benzothiazoles as AcrAB-TolC Efflux Pump Inhibitors in E. coli", SAR and QSAR in Environmental Research, 26(10), 853-871 (2015). DOI:10.1080/1062936X.2015.1106581
  8. O. Unsalan, Y. Sert, H. Ari, A. Simão, A. Yilmaz, M. Boyukata, O. Bolukbasi, K. Bolelli, I. Yalcin, “Micro-Raman, Mid-IR, Far-IR and DFT studies on 2-[4-(4-Fluorobenzamido)phenyl] benzothiazole”, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 125: 414-421, (May, 2014). DOI: 10.1016/j.saa.2014.01.118
  9. Tuğba Ertan-Bolelli, Yaman Musdal, Kayhan Bolelli, Serap Yilmaz, Yasemin Aksoy, Ilkay Yildiz, Esin Aki-Yalcin, and Ismail Yalcin, “Synthesis, Biological Evaluation of 2-Substituted-5-(4-nitrophenylsulfonamido) benzoxazoles as Human GST P1-1 Inhibitors and Description of the Binding Site Features”, ChemMedChem, 9(5-SI): 984-992, (May, 2014). DOI: 10.1002/cmdc.201400010
  10. Serap Yilmaz, Gulsen Altinkanat-Gelmez, Kayhan Bolelli, Deniz Guneser-Merdan, M. Ufuk Over-Hasdemir, Ilkay Yildiz, Esin Aki-Yalcin, Ismail Yalcin, “Pharmacophore Generation of 2-Substituted Benzothiazoles as AdeABC Efflux Pump Inhibitors in A. baumannii”, SAR and QSAR in Environmental Research, 25(7): 551-563, (2014). DOI: 10.1080/1062936X.2014.919357
  11. Bhagyasree JB; Varghese, Hema T; Panicker CY; Samuel, Jadu; Van Alsenoy, Christian; Bolelli, Kayhan; Yildiz, Ilkay; Aki, Esin, “Vibrational spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations and computational study of 5-nitro-2-(4-nitrobenzyl) benzoxazole”, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 102C: 99-113, (Feb, 2013). DOI: 10.1016/j.saa.2012.09.032
  12. Yaman Musdal, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yılmaz, Deniz Ceyhan, Usama Hegazy, Bengt Mannervik, Yasemin Aksoy,  “Inhibition of human glutathione transferase P1-1 by novel benzazole derivatives”, Turkish Journal of Biochemistry, 37(4): 431-436, (30 December 2012). DOI: 10.5505/tjb.2012.30301
  13. Kayhan Bolelli, Ismail Yalcin, Tugba Ertan-Bolelli, Selda Ozgen, Fatma Kaynak-Onurdag, Ilkay Yildiz, Esin Aki, “Synthesis of novel 2-[4-(4-substitutedbenzamido/ phenylacetamido)phenyl]benzothiazoles as antimicrobial agents”, Medicinal Chemistry Research, 21(11): 3818-3825, (Nov, 2012). DOI: 10.1007/s00044-011-9918-4
  14. T. Ertan, I. Yildiz, B. Tekiner-Gulbas, K. Bolelli, O. Temiz-Arpaci, S. Ozkan, F. Kaynak, I. Yalcin, E. Aki, “Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents”, European Journal of Medicinal Chemistry, 44(2): 501-510, (Feb, 2009). DOI: 10.1016/j.ejmech.2008.04.001
  15. I. Yildiz, T. Ertan, K. Bolelli, O. Temiz-Arpaci, I. Yalcin, E. Aki, “QSAR and pharmacophore analysis on amides against drug-resistant S. aureus”, SAR and QSAR in Environmental Research, 19(1-2): 101-113, (2008). DOI: 10.1080/10629360701844159

Short Communications

  1. Ismail Yalcin, Serap Yilmaz, Kayhan Bolelli, Esin Aki-Yalcin, Ufuk Over-Hasdemir, “Binding site description of 2-substituted benzothiazoles as potential RND efflux pump inhibitors”, Macedonian pharmaceutical bulletin, 62 (suppl): 543-544, (2016).
  2. Esin Aki-Yalcin, Ozum Ozturk, Kayhan Bolelli, Ismail Yalcin, “Docking studies of neurokinin-1 receptor antagonists as an anticancer target”, Macedonian pharmaceutical bulletin, 62 (suppl): 553-554, (2016).

Proceeding Papers

  1. Mustafa Lawar, Ismail Yalcin, Kayhan Bolelli, Hakan Sezgin Sayiner, Fatma Kandemirli, “QSAR Study on Thiosemicarbazone Derivatives as Ribonucleotide Reductase Inhibitors”, Electronic Letters on Science&Engineering, 13(2) Special Issue: p37-38, (2017).
  2. Oksuzoğlu E., Foto E., Zilifdar F., Ertan-Bolelli T., Bolelli K., “A study on antiproliferative and genotoxic potentials in L929 and HeLa cell lines -the mutagenic activities in Salmonella strains of novel 2,5-disubstitutedbenzoxazole derivatives”, The FEBS Journal, 283 (Suppl. 1): 85, (2016). DOI: 10.1111/febs.13807.
  3. Fatma Zilifdar, Egemen Foto, Omur Bostanci, Sibel Sari, Kayhan Bolelli, Ismail Yalcin, Nuran Diril, “Mutagenic Activity of 4 Newly Synthesized Heterocyclic Compounds”, The Turkish Journal of Occupational / Environmental Medicine and Safety (TURJOEM), 1(1), Suppl. 1: 14, (2015).
  4. Egemen Foto, Fatma Zilifdar, Sibel Sari, Omur Bostanci, Kayhan Bolelli, Ismail Yalcin, Nuran Diril, “Mutagenic Activity of Some Benzothiazole Derivatives”, The Turkish Journal of Occupational / Environmental Medicine and Safety (TURJOEM), 1(1), Suppl. 1: 16, (2015).
  5. Esin Aki, Ismail Yalcin, Ilkay Yildiz, Ozlem Temiz-Arpaci, Kayhan Bolelli, Tugba Ertan-Bolelli, “DNA-Topoisomerase Inhibitory Activity of Some Heterocyclic Compounds and Their Structure-Activity Relationships”, Medicinal Chemistry Research, 19(S1): 6, (Feb, 2010).

Oral Presentations:

  1. Ismail Yalcin, Kayhan Bolelli, Esin Aki-Yalcin, Yaman Musdal, Bengt Mannervik. Structure-Activity Relationship Analysis of Some New Benzothiazole Derivatives as hGST P1-1 Enzyme Inhibitors, 9th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI 2017), Bogmallo Beach Resort, Goa, India, IL-13: p32, 27-30 October 2017.
  2. Ismail Yalcin, Serap Yılmaz, Kayhan Bolelli, Ozum Ozturk, Esin Aki-Yalcin. Structure-Activity Relationship Analysis of Some Benzazoles as Topo II Enzyme Inhibitors, 5th International BAU Drug Design Congress, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, IS-18: p27, 19-21 October 2017.
  3. Esin Aki-Yalcin, Serap Yilmaz, Kayhan Bolelli, Ozum Ozturk, Andry Nur Hidayat, Ismail Yalcin. Computer Aided Drug Design Studies on Benzazoles Active against Topo II Enzyme as an Anticancer Target, 2nd International Gazi Symposium Series (GPSS 2), Gazi University Faculty of Pharmacy, Ankara, Turkey, O41: p67, 11-13 October 2017.
  4. Mustafa Lawar, Ismail Yalcin, Kayhan Bolelli, Hakan Sezgin Sayiner, Fatma Kandemirli. QSAR Study on Thiosemicarbazone Derivatives as Ribonucleotide Reductase Inhibitors, Sixth Bozok Science Workshop (BSW 2017), Bozok University, Art and Science Faculty, Yozgat, Turkey, p37-38, 23-25 August 2017.
  5. Ismail Yalcin, Kayhan Bolelli, Esin Aki-Yalcin, Yaman Musdal, Bengt Mannervik. Binding Site Description Analysis of Some New Benzothiazole Derivatives as hGST P1-1 Enzyme Inhibitors, 17th Hellenic Symposium on Medicinal Chemistry (HSMC-2017), Aristotle University of Thessaloniki, Thessaloniki, Greece, ML8: p13, 1-3 June 2017.
  6. Ismail Yalcin, Serap Yilmaz, Kayhan Bolelli, Esin Aki-Yalcin. Binding Site Description Studies of 2-Substituted Benzothiazoles as the Novel RND Efflux Pump Inhibitors, 4rd International Conference on Computation for Science and Technology (ICCST) 2016, De Baron Resort, Langkawi, Malaysia, PLN5: p49, 3-4 November 2016.
  7. Ismail Yalcin, Kayhan Bolelli, Yaman Musdal, Esin Aki-Yalcin. Structure-Activity Relationship Analysis of Some New Benzothiazole Derivatives as hGST P1-1 Enzyme Inhibitors, 4th International BAU Drug Design Congress, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, IS-24: p32, 13-15 October 2016.
  8. Emine Oksuzoğlu, Egemen Foto, Fatma Zilifdar, Tugba Ertan-Bolelli, Kayhan Bolelli. A study on antiproliferative and genotoxic potentials in L929 and HeLa cell lines -the mutagenic activities in Salmonella strains of novel 2,5-disubstitutedbenzoxazole derivatives, 41st FEBS Congress, Ephesus, Kuşadası, Turkey, ST-05.01.1-004: p85, 03-08 September 2016.
  9. Esin Akı Yalçın, Serap Yılmaz, Kayhan Bolelli, Özüm Öztürk, Tuğba Ertan-Bolelli, İsmail Yalçın, The Role of Chemometrics in Computer Aided Drug Design Studies, 3rd International Conference on New Trends in Chemometrics and Applications (NTCA-2016), Side, Antalya, Turkey, IL-02: p4, May 25-28, 2016.
  10. Özüm Öztürk, Esin Akı-Yalçın, Kayhan Bolelli, İsmail Yalçın. Nörokinin-1 Reseptör Antagonistlerinin Moleküler Modelleme Çalışmaları, 2. Bilgisayar Destekli İlaç Tasarımı Kursu (Uygulamalı), Biruni Üniversitesi, İstanbul, Türkiye, S-2: p11, 16-17 Mayıs 2016.
  11. Kayhan Bolelli, Yaman Musdal, Esin Aki-Yalcin, Ismail Yalcin. Bazı Yeni Benzotiyazol Türevi Bileşiklerin GST Enzimi üzerine Etkileri ve Doking Çalışmaları, 2. Bilgisayar Destekli İlaç Tasarımı Kursu (Uygulamalı), Biruni Üniversitesi, İstanbul, Türkiye, S-9: p19, 16-17 Mayıs 2016.
  12. Esin Aki-Yalcin, Ismail Yalcin, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, Ozum Ozturk. Molecular Modeling Application by using Discovery Studio, BIOVIA Turkish Regional User Meeting with A-Ztech Ltd., ByOtell Hotel, Istanbul, Turkey, 6 May 2016.
  13. Ismail Yalcin, Serap Yilmaz, Kayhan Bolelli, Ozum Ozturk and Tugba Ertan Bolelli. Enzyme Binding Site Description of AcrAB-TolC Efflux Pump Inhibitors, 10th AFMC International Medicinal Chemistry Symposium (AIMECS 2015), International Convention Center Jeju, Jeju, Korea, OP4-1: p253, 18-21 October 2015.
  14. E. Aki-Yalcin, O. Ozturk, T. Ertan-Bolelli, K. Bolelli, S. Yilmaz, A. H. Nur, O. Bingol-Ozakpinar, and F. Ozdemir. Mechanism of Action of Some New Anticancer Active Neurokinin-1 (NK1) Receptor Antagonists, 10th AFMC International Medicinal Chemistry Symposium (AIMECS 15), International Convention Center Jeju, Jeju, Korea, OP4-4: p256, 18-21 October 2015.
  15. Ismail Yalcin, Serap Yilmaz, Gulsen Altinkanat-Gelmez, Kayhan Bolelli, Deniz Guneser-Merdan, M. Ufuk Over-Hasdemir, Esin Aki-Yalcin. Binding Site Description Of Benzothiazoles As the RND Efflux Pump Acrb Inhibitors, 3rd International BAU-Drug Design Symposium 2015, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, CL-14: p30, 1-3 October 2015.
  16. Esin Aki-Yalcin, Ozum Ozturk, Kayhan Bolelli, Tugba Ertan-Bolelli, Andry Nur Hidayat, Ozlem Bingol-Ozakpinar, Filiz Ozdemir, Ismail Yalcin. Mechanism of Action of Neurokinin-1 Receptors as an Anticancer Target, 3rd International BAU-Drug Design Symposium 2015, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, CL-22: p39-40, 1-3 October 2015.
  17. Ismail Yalcin, Serap Yilmaz, Kayhan Bolelli, Ozum Ozturk, Tugba Ertan-Bolelli, Esin Aki-Yalcin. Description of the Binding Site Features of AcrAB-TolC Efflux Pump Inhibitors, 8th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2015), Chios, Greece, MT-11: p44, 21-25 June 2015.
  18. Esin Akı-Yalcin, Ozum Ozturk, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, A.H. Nur, S. Sahin, Ismail Yalcin, Ozlem Bingol-Ozakpinar, Filiz Ozdemir. Molecular Modeling Studies on Neurokinin 1 (NK1) Receptors, 8th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2015), Chios, Greece, MT-12: p47, 21-25 June 2015.
  19. Esin Aki-Yalcin, Ismail Yalcin, Tugba Ertan-Bolelli, Serap Yilmaz, Kayhan Bolelli, Özüm Öztürk, Tugba Taskin-Tok, Emine Öksüzoglu, Cigdem Özen-Kaplan. Computer aided drug design studies for new anticancer drugs, EACR-Sponsored 3rd Anticancer Agent Development Congress, Dokuz Eylül University, Izmir, Turkey, Closing Lecture: p38, 18-19 May 2015.
  20. Ozum Ozturk, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, Ismail Yalcin, Esin Aki-Yalcin. Molecular Docking Analysis of Benzothiazole/Benzothiazolium Derivatives as Human DNA Topoisomerase II Inhibitors, BIOVIA Turkish Regional User Meeting with A-Ztech Ltd., ByOtell Hotel, Istanbul, Turkey, 10 April 2015.
  21. Ismail Yalcin, Tugba Ertan-Bolelli, Yaman Musdal, Kayhan Bolelli, Serap Yilmaz, Yasemin Aksoy, Bengt Mannervik, Ilkay Yildiz, Esin Aki-Yalcin. Computer Aided Molecular Modeling of the Binding Site and GSH Conjugation Features of the New Human GST P1-1 Inhibitors, The 3rd International Conference on Computation for Science and Technology, Aston Denpasar Hotel and Convention Center, Bali, Indonesia, PL-03: p6, 23-25 September 2014.
  22. Esin Aki-Yalcin, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, Ozum Ozturk, Tugba Taskin-Tok, Andry Nur Hidayat, Ilkay Yildiz, Ismail Yalcin. Anticancer Drug Design Studies using Molecular Modeling Techniques, The 3rd International Conference on Computation for Science and Technology, Aston Denpasar Hotel and Convention Center, Bali, Indonesia, IS-02: p10, 23-25 September 2014.
  23. Tugba Ertan-Bolelli, Ismail Yalcin, Yaman Musdal, Serap Yilmaz, Kayhan Bolelli, Ozum Ozturk, Yasemin Aksoy, Bengt Mannervik, Ilkay Yildiz, Esin Aki-Yalcin. Molecular Docking Studies on Human Glutathione S-transferase Enzyme (hGSTP1-1), The 3rd International Conference on Computation for Science and Technology, Aston Denpasar Hotel and Convention Center, Bali, Indonesia, O-P13: p28, 23-25 September 2014.
  24. Serap Yilmaz, Tugba Ertan-Bolelli, Kayhan Bolelli, Ozum Ozturk, Sanaz Ataei, Ilkay Yildiz, Esin Aki-Yalcin, Ismail Yalcin. Computational Drug Design Studies for Multidrug Resistance AcrAB-TolC Efflux Pump Inhibitors on Escherichia coli, The 3rd International Conference on Computation for Science and Technology, Aston Denpasar Hotel and Convention Center, Bali, Indonesia, O-P106: p62, 23-25 September 2014.
  25. Esin Aki-Yalcin, Tugba Ertan-Bolelli, Tugba Taskin-Tok, Cigdem Ozen, Kayhan Bolelli, Serap Yilmaz, Ozum Ozturk, Ilkay Yildiz, Ismail Yalcin. Identification of Mechanism of Action of DNA-Topoisomerase II Inhibitors by Molecular Modeling Studies, 20th European Symposium on Quantitative Structure-Activity Relationships (20th EuroQSAR), St-Petersburg, Russia, OC12: p52, 31 August - 4 September 2014.
  26. Ismail Yalcin, Tugba Ertan-Bolelli, Yaman Musdal, Kayhan Bolelli, Serap Yilmaz, Yasemin Aksoy, Bengt Mannervik, Ilkay Yildiz, Esin Aki-Yalcin. Description of the Binding Site Features of Some Fused Heterocycles as New Human GST P1-1 Inhibitors, 2nd International BAU-Drug Design Symposium 2014, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, CL-5: p9, 17-19 April 2014.
  27. Esin Aki-Yalcin, Tugba Ertan-Bolelli, Tugba Taskin-Tok, Serap Yilmaz, Kayhan Bolelli, Ozum Ozturk, Ilkay Yildiz and Ismail Yalcin. Molecular Modeling Studies on DNA-Topoisomerase II Inhibitors, 2nd International BAU-Drug Design Symposium 2014, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, IL-8: p18, 17-19 April 2014.
  28. Esin Aki-Yalcin, Ismail Yalcin, Ilkay Yildiz, Tuğba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, Özüm Öztürk. Chemometrics in Drug Design, 2nd International Conference on New Trends in Chemometrics and Applications (NTCA-2013), Ankara University, Faculty of Pharmacy, Ankara, Turkey, IL-05: p7, 25-28 October 2013.
  29. Esin Aki-Yalcin, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, Ozum Ozturk, Tugba Taskin-Tok, Ilkay Yildiz and Ismail Yalcin. Rational Design of DNA-Topoisomerase Inhibitory Active Benzazoles as Antitumoral Agents, 9th AFMC International Medicinal Chemistry Symposium (AIMECS 13), The Grand Hotel, Taipei, Taiwan, O-37: p54, 15-18 October 2013.
  30. Ismail Yalcin, Kayhan Bolelli, Serap Yilmaz, Tugba Ertan-Bolelli, Ozum Ozturk, Sanaz Ataei, Ilkay Yildiz, Esin Aki-Yalcin. CADD Studies on Chemotherapeutical Active Fused Heterocyclic Compounds, 9th AFMC International Medicinal Chemistry Symposium (AIMECS 13), The Grand Hotel, Taipei, Taiwan, S18-01: p55, 15-18 October 2013.
  31. Esin Aki, Tugba Taskin, Serap Yilmaz, Tugba Ertan-Bolelli, Kayhan Bolelli, Ozum Ozturk, Ilkay Yildiz, Ismail Yalcin, Yaman Musdal, Yasemin Aksoy. Molecular Modelling Studies on the Design of Chemotherapeutically Active Heterocyclic Compounds, 1st International BAU-Drug Design Symposium 2013, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, Lecture-1: p26, 21-23 March 2013.
  32. Ismail Yalcin, Serap Yilmaz, Kayhan Bolelli, Tugba Ertan-Bolelli, Ilkay Yildiz, Esin Aki-Yalcin. Common Feature Pharmacophore Generation of Heterocyclic Compounds as Bacterial RND Efflux Pump Inhibitors, 1st International BAU-Drug Design Symposium 2013, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, Lecture-2: p27, 21-23 March 2013.
  33. Ismail Yalcin, Esin Aki, Ilkay Yildiz, Tugba Ertan-Bolelli, Kayhan Bolelli, and Serap Yilmaz. Computational Methods in Rational Drug Design, 2nd International Conference on Computation for Science and Technology (ICCST-II), Nigde, Turkey, Plenary Lec-5: p43, 09-11 July 2012.
  34. Esin Akı, İsmail Yalçın, Ilkay Yildiz, Tuğba Taşkın, Tuğba Ertan-Bolelli, Serap Yilmaz, Kayhan Bolelli. Structure Based Drug Design Methods, 2nd International Conference on Computation for Science and Technology (ICCST-II), Nigde, Turkey, Invited Lec-7: p52, 09-11 July 2012.
  35. Ismail Yalcin, Esin Aki, Ilkay Yildiz, Tugba Ertan-Bolelli, Kayhan Bolelli, and Serap Yilmaz. QSAR and Molecular Modeling Studies on Chemotherapeutic Active Benzazoles, 8th AFMC International Medicinal Chemistry Symposium (AIMECS 11), Keio Plaza Hotel, Tokio, Japan, IL-B1: p8, 29 November-2 December 2011.
  36. Esin Aki, Ismail Yalcin, Ilkay Yildiz, Betul Tekiner-Gulbas, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, Sanaz Ataei, Özüm Öztürk. Chemometrics in Drug Design, 1st International Conference on New Trends in Chemometrics and Applications (NTCA-2011), Side, Antalya, Turkey, IL-05: p7, October 08-11, 2011.
  37. Ismail Yalcin, Kayhan Bolelli, Serap Yilmaz, İlkay Yildiz, and Esin Aki-Yalcin. Common Feature Pharmacophore Generation of Heterocyclic Compounds against Efflux Pump Over-expressor Bacteria, 6th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2011), Maribor, Slovenia, OC-21: p67, 03-07 September 2011.
  38. Esin Aki, Tugba Taskin, Yaman Musdal, Yasemin Aksoy, Serap Yilmaz, Tugba Ertan-Bolelli, Kayhan Bolelli, İlkay Yildiz, İsmail Yalcin. Docking Studies of GST Inhibitory Active 2-Substituted Benzazoles, 6th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2011), Maribor, Slovenia, MT-07: p43, 03-07 September 2011.
  39. Esin Akı, İsmail Yalçın, İlkay Yıldız, Tugba Ertan-Bolelli, Kayhan Bolelli, Tugba Taşkın, Serap Yılmaz. Kemoterapötik Etkili Heterosiklik Bileşiklerin Bilgisayar Destekli İlaç Tasarım Çalışmaları, Uluslararası Katılımlı 25. Ulusal Kimya Kongresi (UKK-25), Atatürk Üniversitesi, Erzurum, Türkiye, IL-009: p43, 27 Haziran - 02 Temmuz 2011.
  40. Tugba Taskin-Tok, Esin Akı, Ismail Yalcin, Ilkay Yildiz, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yılmaz. Docking Studies of Topoisomerase II Inhibitors, Uluslararası Katılımlı 25. Ulusal Kimya Kongresi (UKK-25), Atatürk Üniversitesi, Erzurum, Türkiye, MS-013: p180, 27 Haziran - 02 Temmuz 2011.
  41. Esin Aki, İsmail Yalçin, İlkay Yildiz, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz. Computational Drug Design Studies on Antitumoral Active Heterocyclic Compounds, 18th European Symposium on Quantitative Structure-Activity Relationships (18th EuroQSAR), Rhodes, Greece, OP27: p84, 19-24 September 2010.
  42. Esin Akı, İsmail Yalçın, İlkay Yildiz, Tuğba Ertan-Bolelli, Kayhan Bolelli, Serap Yılmaz. Computer Aided Drug Design Studies on Chemotherapeutically Active Heterocyclic Compounds, Third International Meeting on Pharmacy & Pharmaceutical Sciences (IMPPS-3), Istanbul, Turkey, PL-2: p16, 9-12 June 2010.
  43. Esin Aki, İsmail Yalcin, İlkay Yildiz, Özlem Temiz-Arpaci, Kayhan Bolelli, Tugba Ertan-Bolelli. DNA-Topoisomerase Inhibitory Activity of Some Heterocyclic Compounds and Their Structure-Activity Relationships, Current Trends in Drug Discovery Research (CTDDR-2010), Med Chem Res (2010), Lucknow, India, 19(Suppl.1): S6, 17-21 February 2010.
  44. Ilkay Yıldız, Tugba Ertan, Ozlem Temiz-Arpaci, Kayhan Bolelli, Esin Aki-Sener, Ismail Yalcin. Three-Dimensional Common-Feature Hypotheses and 2D-QSAR Studies on Some Antimicrobiologically Active Amides against Drug-Resistance Staphylococcus aureus, Fourth International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2007), Moscow, Russia, OC-15: p52, 1-5 September 2007.

Poster Presentations:

  1. T. Ertan-Bolelli, K. Bolelli, Y. Musdal, I. Yildiz, E. Aki Yalcin, B. Mannervik, I. Yalcin. Docking studies of 2-substituted-5-(4-trifluoromethylphenylsulfonamido) benzoxazole derivatives on human GST P1-1 enzyme, The 69th Southeastern Regional Meeting of the American Chemical Society (SERMACS 2017), Sheraton Charlotte Hotel, Charlotte, NC, USA, 95: p36, November 7-11, 2017.
  2. K. Bolelli,T. Ertan-Bolelli, I. Yalcin. Docking studies of some benzothiazole derivatives on aldose reductase enzyme, The 69th Southeastern Regional Meeting of the American Chemical Society (SERMACS 2017), Sheraton Charlotte Hotel, Charlotte, NC, USA, 98: p36, November 7-11, 2017.
  3. Kayhan Bolelli, Ismail Yalcin, Tugba Ertan-Bolelli, Yaman Musdal, Bengt Mannervik, Esin Aki-Yalcin. Microwave Synthesis and hGST P1-1 Enzyme Inhibitor Activities of Some Novel Benzothiazole Deivatives, 9th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI 2017), Bogmallo Beach Resort, Goa, India, P-02: p51, 27-30 October 2017.
  4. Kayhan Bolelli, Tugba Ertan-Bolelli, Bilgehan Dogru*, Ilkay Yildiz. Molecular Docking Studies of 2,5-Disubstituted Benzoxazole Derivatives as Aldose Reductase Enzyme Inhibitor, 3rd International Turkic World Conference on Chemical Sciences and Technologies (ITWCCST2017), Baku, Azerbaijan, PO-19: p163, September 10-13, 2017.
  5. Kayhan Bolelli, Hatice Ari, Mustafa Boyukata, Ismail Yalcin, Ozan Unsalan. Molecular Structure and Vibrational Spectroscopic Study of 2-[4-(4-Nitrobenzamido)phenyl]benzothiazole using DFT Method, III. International Turkish Congress on Molecular Spectroscopy (TURCMOS 2017), Nasuhoglu Cultural Center, Mugla University, Bodrum, Turkey, P-036: p157, 26-29 August 2017.
  6. Ismail Yalcin, Kayhan Bolelli, Yaman Musdal, Bengt Mannervik, Esin Aki-Yalcin. Binding Properties of Some New hGST P1-1 Inhibitor Benzothiazoles, 11th AFMC International Medicinal Chemistry Symposium (AIMECS2017), Melbourne, Australia, p86, 23-26 July 2017.
  7. Ozum Ozturk, Esin Aki-Yalcin, Kayhan Bolelli, Ismail Yalcin. Molecular Docking Studies Of Neurokinin-1 Receptor Antagonists, 11th AFMC International Medicinal Chemistry Symposium (AIMECS2017), Melbourne, Australia, p128, 23-26 July 2017.
  8. Kayhan Bolelli, Ismail Yalcin, Esin Aki-Yalcin, Tugba Ertan-Bolelli, Yaman Musdal, Bengt Mannervik. Synthesis, Structure Elucidation and hGSTP1-1 Inhibitor Activity of Some Benzothiazoles, 11th AFMC International Medicinal Chemistry Symposium (AIMECS2017), Melbourne, Australia, p170, 23-26 July 2017.
  9. Kayhan Bolelli, Ismail Yalcin, Tugba Ertan-Bolelli, Esin Aki-Yalcin, Yaman Musdal, Bengt Mannerick. Design, Synthesis and Structure Elucidation of Some Novel Benzothiazole Derivatives, as the hGSTP1-1 Enzyme Inhibitors, 17th Hellenic Symposium on Medicinal Chemistry (HSMC-2017), Aristotle University of Thessaloniki, Thessaloniki, Greece, P10: p52, 1-3 June 2017.
  10. Kayhan Bolelli, Tugba Ertan-Bolelli, Ismail Yalcin. Pharmacophore Identification Analysis on Known SIRT1 Enzyme Activators, 2nd Scripps Florida Symposium on Biology of Aging: Advances in Therapeutic Approaches to Extend Healthspan, The Scripps Research Institute, Jupiter, Florida, USA, P-3: p3, January 22-25, 2017.
  11. Tugba Ertan-Bolelli, Kayhan Bolelli, Ilkay Yildiz. Molecular Docking Studies on SIRT1 Enzyme, 2nd Scripps Florida Symposium on Biology of Aging: Advances in Therapeutic Approaches to Extend Healthspan, The Scripps Research Institute, Jupiter, Florida, USA, P-9: p9, January 22-25, 2017.
  12. Kayhan Bolelli, Ismail Yalcin, Yaman Musdal, Esin Aki-Yalcin. Design and Synthesis of Some New Benzothiazole Derivatives, as the hGSTP1-1 Enzyme Inhibitors, 4th International BAU Drug Design Congress, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, PP-70: p213, 13-15 October 2016.
  13. Ismail Yalcin, Serap Yilmaz, Kayhan Bolelli, Esin Aki-Yalcin, Ufuk Over-Hasdemir. Binding site description of 2-substituted benzothiazoles as potential RND efflux pump inhibitors, 6th Congress of Pharmacy in Macedonia, Ohrid, Macedonia, S6 PP 259: p571-572, June 1-5, 2016.
  14. Esin Aki-Yalcin, Ozum Ozturk, Kayhan Bolelli, Ismail Yalcin. Docking studies of neurokinin-1 receptor antagonists as an anticancer target, 6th Congress of Pharmacy in Macedonia, Ohrid, Macedonia, S6 PP 264: p553-554, June 1-5, 2016.
  15. Kayhan Bolelli, Yaman Musdal, Esin Aki-Yalcin, Ismail Yalcin. Docking Studies of Some Heterocyclic Compounds on Glutation S-Transferase Enzyme, 3rd International Conference on New Trends in Chemometrics and Applications (NTCA-2016), Side, Antalya, Turkey, PP-74: p156, May 25-28, 2016.
  16. Tugba Ertan-Bolelli, Yaman Musdal, Bengt Mannervik, Kayhan Bolelli, Serap Yilmaz, Ozum Ozturk, Ilkay Yildiz, Esin Aki-Yalcin, Ismail Yalcin. Design and Synthesis of Novel sulfonamide-containing benzoxazoles as Human GST P1-1 Inhibitors, Challenges in Organic Chemistry (ISACS19), Irvine, Los Angeles, California, USA, P15, 20-23 March 2016.
  17. Kayhan Bolelli, Tugba Ertan-Bolelli, Serap Yilmaz, Ozum Ozturk, Esin Aki-Yalcin, Ismail Yalcin. Pharmacophore Identification Analysis on hGST P1-1 Enzyme Inhibitory Active Benzothiazole Derivatives, Challenges in Organic Chemistry (ISACS19), Irvine, Los Angeles, California, USA, P33, 20-23 March 2016.
  18. Ozum Ozturk, Esin Aki-Yalcin, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, Ismail Yalcin. Molecular Modeling Studies of Neurokinin-1 Receptor Antagonists, The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem-2015), Honolulu, Hawaii, USA, 10-HLTH-450: p294, 15-20 December 2015.
  19. Serap Yilmaz, Ozum Ozturk, Kayhan Bolelli, Tugba Ertan Bolelli, Esin Aki Yalcin, Ismail Yalcin. Molecular Docking Studies of Some Novel Bacterial Topoisomerase II Inhibitors, The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem-2015), Honolulu, Hawaii, USA, 10-HLTH-454: p295, 15-20 December 2015.
  20. Serap Yilmaz, Ozum Ozturk, Kayhan Bolelli, Tugba Ertan Bolelli, Esin Aki Yalcin, Ismail Yalcin. Pharmacophore Generation of Some Novel Benzothiazole Derivatives as Bacterial Topoisomerase II Inhibitors, 10th AFMC International Medicinal Chemistry Symposium (AIMECS 15), International Convention Center Jeju, Jeju, Korea, PP2-39: p293, 18-21 October 2015.
  21. Gizem Kunal, Filiz Arioz-Ozdemir, Ozlem Bingol-Ozakpinar, Kayhan Bolelli, Esin Aki-Yalcin, Ismail Yalcin. A New Rapid RP-HPLC Method For Determination Of Novel 2-[4-(4-Ethyl Benzamido)Phenyl]-Benzothiazole, 3rd International BAU-Drug Design Symposium 2015, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, PP-74: p195-196, 1-3 October 2015.
  22. Kayhan Bolelli, Hatice Ari, Mustafa Boyukata, Ismail Yalcin, Ozan Unsalan. Micro-Raman, Mid-IR and DFT Studies on 2-[4-(4-Ethylbenzamido)phenyl]benzothiazole, II. International Turkish Congress on Molecular Spectroscopy (TURCMOS 2015), Akdeniz University, Antalya, Turkey, P-136: p215, 13-18 September 2015.
  23. Ozum Ozturk, Esin Aki-Yalcin, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, Ismail Yalcin. Common Pharmacophore Generation of Some Antitumor Agents, 8th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2015), Chios, Greece, PO-1-02: p55, 21-25 June 2015.
  24. Kayhan Bolelli, Tugba Ertan-Bolelli, Ozlem Bingol-Ozakpinar, Filiz Arioz-Ozdemir, Ismail Yalcin, Esin Aki-Yalcin. Cytotoxic Activity of Some Benzazole Derivatives, 8th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2015), Chios, Greece, PO-1-07: p60, 21-25 June 2015.
  25. Serap Yilmaz, Ozum Ozturk, Kayhan Bolelli, Tugba Ertan-Bolelli, Dilara Eren, Esin Aki-Yalcin, Ismail Yalcin. Comparison of Pharmacophore Models between Fluoroquinolones and Nonfluoroquinolone Bacterial Type II Topoisomerase Inhibitors, 8th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2015), Chios, Greece, PO-2-14: p67, 21-25 June 2015.
  26. Kayhan Bolelli, Tugba Ertan-Bolelli, Ozlem Bingol-Ozakpinar, Filiz Arioz-Ozdemir, Esin Aki-Yalcin, Ismail Yalcin. Anticancer activity of some heterocyclic compounds, EACR-Sponsored 3rd Anticancer Agent Development Congress, Dokuz Eylül University, Izmir, Turkey, PP-072: p129, 18-19 May 2015.
  27. Ozum Ozturk, Esin Akı-Yalçın, Tuğba Ertan-Bolelli, Kayhan Bolelli, Serap Yılmaz, İsmail Yalçın. Pharmacophore generation of neurokinin-1 receptor antagonists as antitumor agents, EACR-Sponsored 3rd Anticancer Agent Development Congress, Dokuz Eylül University, Izmir, Turkey, PP-094: p151, 18-19 May 2015.
  28. Tugba Ertan-Bolelli, Kayhan Bolelli, Yaman Musdal, Bengt Mannervik, Esin Aki-Yalcin, Ismail Yalcin. Molecular modeling studies on human glutathione-S-transferase enzyme, EACR-Sponsored 3rd Anticancer Agent Development Congress, Dokuz Eylül University, Izmir, Turkey, PP-119: p176, 18-19 May 2015.
  29. Ilkay Yildiz, Tugba Ertan-Bolelli, Sanaz Ataei, Serap Yilmaz, Esin Karatas, Kayhan Bolelli, Ozum Ozturk, Ismail Yalcin. Molecular Docking and Pharmacophore Analysis on some Topoisomerase I Targetted Antitumor Benzoxazole and Analogues, 9th Drug Design & Medicinal Chemistry, Berlin, Germany, 5-6 May 2015.
  30. Tubanur Ustaömer-Dere, Kayhan Bolelli, İlkay Yıldız. Yataklı Tedavi Hizmetlerinde Klinik Eczacının Yeri ve Önemi, Kamu Eczacıları Kongresi, Bilkent Otel, Ankara, Türkiye, 6-7 Mart 2015.
  31. Fatma Zilifdar, Egemen Foto, Omur Bostanci, Sibel Sari, Kayhan Bolelli, Ismail Yalcin, Nuran Diril. Mutagenic Activity of 4 Newly Synthesized Heterocyclic Compounds, 1st International Congress & Workshop of Forensic Toxicology (1st ForeTox 2014), Ankara, Turkey, P14: p71, 29-30 November 2014.
  32. Egemen Foto, Fatma Zilifdar, Sibel Sari, Omur Bostanci, Kayhan Bolelli, Ismail Yalcin, Nuran Diril. Mutagenic Activity of Some Benzothiazole Derivatives, 1st International Congress & Workshop of Forensic Toxicology (1st ForeTox 2014), Ankara, Turkey, P16: p73, 29-30 November 2014.
  33. Kayhan Bolelli, Ismail Yalcin, Tugba Ertan-Bolelli, Serap Yilmaz, Ozum Ozturk, Ilkay Yildiz, Esin Aki-Yalcin. Pharmacophore Identification Analysis on hGST P1-1 Enzyme Inhibitory Active Benzazole Derivatives, The 3rd International Conference on Computation for Science and Technology, Aston Denpasar Hotel and Convention Center, Bali, Indonesia, P-P12: p76, 23-25 September 2014.
  34. Ozum Ozturk, Esin Aki-Yalcin, Tugba Ertan-Bolelli, Kayhan Bolelli, Serap Yilmaz, Ilkay Yildiz, Ismail Yalcin. Common Feature Pharmacophore Generation of Neurokinin-1 Receptor Antagonists, The 3rd International Conference on Computation for Science and Technology, Aston Denpasar Hotel and Convention Center, Bali, Indonesia, P-P110: p103, 23-25 September 2014.
  35. Serap Yilmaz, Tugba Ertan Bolelli, Kayhan Bolelli, Ozum Ozturk, Sanaz Ataei, Ilkay Yildiz, Esin Aki Yalcin, Ismail Yalcin. Molecular Docking Studies of AcrB Trimeric Multidrug Efflux Pumps, 20th European Symposium on Quantitative Structure-Activity Relationships (20th EuroQSAR), St-Petersburg, Russia, P096: p170, 31 August - 4 September 2014.
  36. Ilkay Yildiz, Tugba Ertan-Bolelli, Serap Yilmaz, Sanaz Ataei, Kayhan Bolelli, Ozum Ozturk, Esin Karatas, Esin Aki-Yalcin, Ismail Yalcin. Molecular Modeling Studies on Some Benzazole Derivatives as Topoisomerase I Poison, 20th European Symposium on Quantitative Structure-Activity Relationships (20th EuroQSAR), St-Petersburg, Russia, P147: p221, 31 August - 4 September 2014.
  37. Ismail Yalcin, Tugba Ertan Bolelli, Yaman Musdal, Kayhan Bolelli, Serap Yilmaz, Yasemin Aksoy, Bengt Mannervik, Ilkay Yildiz, Esin Aki Yalcin. Description of the Binding Site and GSH Conjugation Features of the New Human GST P1-1 Inhibitors, 20th European Symposium on Quantitative Structure-Activity Relationships (20th EuroQSAR), St-Petersburg, Russia, P150: p224, 31 August - 4 September 2014.
  38. J.B. Bhagyasree, Hema Tresa Varghese, C. Yohannan Panicker, Jadu Samuel, Christian Van Alsenoy, Kayhan Bolelli, Ilkay Yildiz, Esin Aki. Vibrational spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations and computational study of 5-nitro-2-(4-nitrobenzyl) benzoxazole, 2nd International Conference on New Trends in Chemometrics and Applications (NTCA-2013), Ankara University, Faculty of Pharmacy, Ankara, Turkey, PP-26: p54, 25-28 October 2013.
  39. Kayhan Bolelli, Ismail Yalcin, Tugba Ertan-Bolelli, Serap Yilmaz, Ozum Ozturk, Yaman Musdal, Ilkay Yildiz and Esin Aki-Yalcin. Molecular Docking Studies of Glutathion S-Transferase Inhibitors, 9th AFMC International Medicinal Chemistry Symposium (AIMECS 13), The Grand Hotel, Taipei, Taiwan, P1-03: p62, 15-18 October 2013.
  40. Serap Yilmaz, Ismail Yalcin, Tugba Ertan-Bolelli, Kayhan Bolelli, Ozum Ozturk, Sanaz Ataei, Ilkay Yildiz, and Esin Aki-Yalcin. Molecular Docking Studies on AcrB Trimeric Multidrug Efflux Pumps of Escherichia coli, 9th AFMC International Medicinal Chemistry Symposium (AIMECS 13), The Grand Hotel, Taipei, Taiwan, P1-04: p63, 15-18 October 2013.
  41. Tugba Ertan-Bolelli, Ilkay Yildiz, Selda Ozgen, Kayhan Bolelli, Serap Yilmaz, Sanaz Ataei, Ozum Ozturk, Esin Aki-Yalcin, and Ismail Yalcin. Molecular Docking Studies on Enoyl-ACP Reductase Enzyme, 9th AFMC International Medicinal Chemistry Symposium (AIMECS 13), The Grand Hotel, Taipei, Taiwan, P1-05: p64, 15-18 October 2013.
  42. Kayhan Bolelli, Tuğba Ertan-Bolelli, Yaman Musdal, Serap Yilmaz, Ozum Ozturk, Yasemin Aksoy, Ilkay Yildiz, Esin Aki, Ismail Yalcin. Docking Studies on Glutathione S-Transferase P1-1 Enzyme, Seventh International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2013), Seoul, South Korea, PO-C-03: p66, 8-12 October 2013.
  43. Tugba Ertan-Bolelli, Ilkay Yildiz, Kayhan Bolelli, Serap Yilmaz, Sanaz Ataei,
    Ozum Ozturk, Selda Ozgen, Esin Aki, Ismail Yalcin. Molecular Docking Studies on Dihydropteroate Synthase Enzyme, Seventh International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2013), Seoul, South Korea, PO-C-09: p72, 8-12 October 2013.
  44. Y. Sheena Mary, K. Raju, Tuğba Ertan Bolelli, Kayhan Bolelli, Ilkay Yıldız, Helena I.S. Nogueira, Carlos M. Granadeiro, Christian Van Alsenoy. FT-IR, FT-Raman, surface enhanced Raman scattering and computational study of 2-[p-fluorobenzyl)-6-nitrobenzoxazole, I. International Turkish Congress on Molecular Spectroscopy (TURCMOS 2013), Harbiye Cultural Center & Museum, Istanbul, TURKEY, P106: p188-189, September 15-20, 2013.
  45. Unsalan, O., Sert, Y., Ari, H., Simão, A., Yilmaz, A., Boyukata, M., Bolukbasi, O., Bolelli, K., Yalcin, I. Micro-Raman, Mid-IR, Far-IR and DFT studies on 2-[4-(4-Fluorobenzamido)phenyl]benzothiazole, I. International Turkish Congress on Molecular Spectroscopy (TURCMOS 2013), Harbiye Cultural Center & Museum, Istanbul, TURKEY, P147: p230, September 15-20, 2013.
  46. Sanaz ATAEI, Serap YILMAZ, Ilkay YILDIZ, Tugba ERTAN-BOLELLI, Kayhan BOLELLI, Ozum OZTURK, Esin AKI-YALCIN, Ismail YALCIN. Molecular nDocking Studies of Some Benzazole Derivatives as DNA Topoisomerase I Inhibitors, 49th International Conference on Medicinal Chemistry (RICT-49), The Conference Center Nice Acropolis, Nice, France, HT006: p182, 3-5 July 2013.
  47. Ozum OZTURK, Esin AKI-YALCIN, Tugba ERTAN-BOLELLI, Kayhan BOLELLI, Serap YILMAZ, Sanaz ATAEI, Ilkay YILDIZ, Ismail YALCIN. Common Feature Pharmacophore Generation of DNA Topoisomerase II Enzyme Inhibitors, 49th International Conference on Medicinal Chemistry (RICT-49), The Conference Center Nice Acropolis, Nice, France, HT094: p268, 3-5 July 2013.
  48. Serap YILMAZ, Ismail YALCIN, Tugba ERTAN-BOLELLI, Kayhan BOLELLI, Ozum OZTURK, Ilkay YILDIZ, Esin AKI-YALCIN. Molecular Modeling and Docking Studies of AcrB Trimeric Multidrug Efflux Pumps, 1st International BAU-Drug Design Symposium 2013, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, P11: p63, 21-23 March 2013.
  49. Ozum OZTURK, Esin AKI-YALÇIN, Tuğba ERTAN-BOLELLİ, Kayhan BOLELLİ, Serap YILMAZ, İlkay YILDIZ, İsmail YALÇIN. Docking Studies of Human Topoisomerase II Enzyme Inhibitors, 1st International BAU-Drug Design Symposium 2013, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, P12: p64, 21-23 March 2013.
  50. Kayhan Bolelli, Ismail Yalcin, Tugba Ertan-Bolelli, Serap Yilmaz, Ozum Ozturk, Ilkay Yildiz, Esin Aki-Yalcin. Docking Studies of Glutathion S-Transferase (GST) Inhibitors, 1st International BAU-Drug Design Symposium 2013, Bahçeşehir University, Faculty of Medicine, Istanbul, Turkey, P13: p65, 21-23 March 2013.
  51. Sibel Sarı, Şerife Ömür Bostancı, Egemen Foto, Kayhan Bolelli, Nuran Diril. Benzotiyazol türevi bileşiklerin Ames Test Sistemi ile mutajenik potansiyellerinin belirlenmesi, IV. Multidisipliner Kanser Kongresi, Prof. Dr. Mete Cengiz Kültür Merkezi, Bursa, Türkiye, 13-16 Aralık 2012.
  52. Emine Öksüzoğlu, Kayhan Bolelli, Tuğba Ertan-Bolelli, Serap Yılmaz, Nuran Diril. A Study on Mutagenic Effects of Novel Benzoxasole Derivative Compounds by Ames/Salmonella Microsomal Test System, 8. Uluslararası Katılımlı Türk Toksikoloji Derneği Kongresi (8.TTDK), Beldibi-Kemer, Antalya, Turkey, P67: p66, 15-18 Kasım 2012.
  53. Kayhan Bolelli, Serap Yilmaz, Ilkay Yildiz, Esin Aki, Ismail Yalcin. Common Feature Pharmacophore Generation of Bacterial AdeABC Efflux Pump Inhibitors, 19th European Symposium on Quantitative Structure-Activity Relationships (19th EuroQSAR), Vienna, Austria, P078: p141, 26-30 August 2012.
  54. Esin Aki, Tugba Taskin, Ismail Yalcin, Yaman Musdal, Yasemin Aksoy, Serap Yilmaz, Tugba Ertan-Bolelli, Kayhan Bolelli, Ilkay Yildiz. Computational Drug Design Studies of Some New GST Inhibitory Active 2-Substituted Benzoxazoles and Benzothiazoles, 19th European Symposium on Quantitative Structure-Activity Relationships (19th EuroQSAR), Vienna, Austria, P093: p156, 26-30 August 2012.
  55. Kayhan Bolelli, Tugba Ertan-Bolelli, Ozum Ozturk, Ilkay Yildiz Esin Aki, Ismail Yalcin. Docking Studies of Some Fused Heterocyclic Compounds into HIV-1 Reverse Transcriptase Enzyme, 19th European Symposium on Quantitative Structure-Activity Relationships (19th EuroQSAR), Vienna, Austria, P095: p158, 26-30 August 2012.
  56. Yasemin Aksoy, Deniz Ceyhan, Yaman Musdal, Esin Akı, Tugba Ertan-Bolelli, Kayhan Bolelli, Ilkay Yildiz, Ismail Yalcin. 2-Substituted Benzazole Derivatives, Suicide Inhibitors For Glutathione S-Transferases and Docking Studies, 7th International Symposium on Health Informatics and Bioinformatics (HIBIT 2012), Perissia Hotel, Urgup, Cappadocia, Nevsehir, Turkey, 19-22 April 2012.
  57. Kayhan Bolelli, Serap Yılmaz, İsmail Yalçın, İlkay Yıldız, Esin Akı. QSAR Analysis of Some 2-Substituted Benzothiazoles as Antibacterial Agents against Multidrug-Resistant Staphylococcus aureus, 1st International Conference on New Trends in Chemometrics and Applications (NTCA-2011), Side, Antalya, Turkey, PP-37: p64, 08-11 October 2011.
  58. Kayhan Bolelli, Tugba Ertan-Bolelli, İsmail Yalcin, Esin Akı, İlkay Yıldız. Bazı Yeni 2-[4-(4-Sübstitüebenzamido)fenil] benzotiyazol Türevlerinin 1H-NMR Spektroskopi Çalışmaları, Uluslararası Katılımlı XII. Ulusal Spektroskopi Kongresi (USK-12), Side, Antalya, Türkiye, P-210: p248, 18-22 Mayıs 2011.
  59. İlkay Yıldız, Sanaz Ataei, Serap Yılmaz, Egemen Foto, Tugba Ertan-Bolelli, Kayhan Bolelli, Nuran Diril, Esin Akı-Yalcin, İsmail Yalcin. Three-Dimensional Common-Feature Hypotheses on Benzoxazine Derivatives as Topoisomerase I Inhibitors, The 18th International Conference on Organic Synthesis (ICOS-18), Bergen, Norway, 377: p54, 1-6 August 2010.
  60. Kayhan Bolelli, İsmail Yalçın. Bazı Yeni 2-[4-(4-Sübstitüebenzamido/Fenilasetamido) fenil]benzotiyazol Türevlerinin Sentezi, Yapılarının Aydınlatılması ve Mikrobiyolojik Aktivite Çalışmaları, II. National Congress of Pharmaceutical Chemistry (UFKK-2), Mersin, Turkey, P-11: p22, 13-15 November 2009.
  61. Tugba Ertan-Bolelli, İlkay Yildiz, Kayhan Bolelli, Betül Tekiner-Gulbas, Serap Yilmaz, Özlem Temiz-Arpaci, Esin Aki and Ismail Yalcin. Pharmacophore Analysis on Some Benzoxazoles against Drug-Resistant Escherichia coli, Fifth International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI-2009), Istanbul, Turkey, PO-41: p108, 4-8 July 2009.
  62. Tugba Ertan-Bolelli, İlkay Yildiz, Kayhan Bolelli, Esin Aki, Ismail Yalcin. Pharmacophore Analysis on Some Benzoxazoles against Drug-Resistant Bacillus subtilis, 45th International Conference on Medicinal Chemistry (RICT-45), University of Orléans, Orléans, France, SL-11: p111, 1-3 July 2009.
  63. Kayhan Bolelli, İsmail Yalcın, Tugba Ertan-Bolelli, İlkay Yıldız, Esin Akı and Fatma Kaynak-Onurdag. Synthesis, Structure Elucidation and Microbiological Activity of Some New 2-[4-(4-SubstitutedPhenylacetamido) phenyl] benzothiazole Derivatives, 45th International Conference on Medicinal Chemistry (RICT-45), University of Orléans, Orléans, France, SL-12: p112, 1-3 July 2009.
  64. Ilkay Yildiz, Tugba Ertan, Kayhan Bolelli, Ozlem Temiz-Arpaci, Ismail Yalcin, Esin Akı-Sener. Molecular Modelling Studies on Some Benzazoles as Eukaryotic DNA Topoisomerase II Inhibitors, 4th Central European Conference Chemistry towards Biology (CTB4), Dobogóko, Hungary, P: p135, 8-11 September 2008.
  65. K. Bolelli, I. Yalcin, T. Ertan, F. Kaynak-Onurdağ, I. Yıldız, Ö. Temiz-Arpacı, E. Akı-Sener, U. Abbasoğlu. Synthesis, Structure Elucidation and Microbiological Activity of Some New 2-[4-(4-Substitutedbenzamido)phenyl] benzothiazole Derivatives, International Meeting on Medicinal and Pharmaceutical Chemsitry (IMMPC-3), WOW Kremlin Palace, Antalya, Turkey, P-61: p96, 16-21 October 2007.
  66. T. Ertan, I. Yıldız, B. Tekiner-Gülbaş, K. Bolelli, O. Temiz-Arpacı, S. Özkan, U. Abbasoğlu. Synthesis and in vitro Antibacterial Activity against Pseudomonas aeruginosa of Some Novel 2-Phenyl Benzoxazoles, 8th International Symposium on Pharmaceutical Sciences (ISOPS-8), Ankara, Turkey, P197: p315, 13-16 June 2006.
  67. T. Ertan, I. Yildiz, K. Bolelli, O. Temiz-Arpaci, B. Tekiner-Gulbas, E. Aki-Sener, I. Yalcin, U. Abbasoglu. Synthesis and Antibacterial Activity of Some 4-Substituted-N-(2-Hydroxy-5(or 6)-nitrophenyl)benzamide Derivatives, International Symposium on Medicinal Chemistry Research and Development 2005 (MCRD 2005), Tusan Hotel, Kuşadası, Turkey, P81: p105, 28 September - 1 October 2005.
This Page is Designed by